If you are familiar with
this product and want to
proceed directly to the order section,
2012, I was introduced to a product designed to enhance the body's
production of nitric oxide that causes blood vessels to be more
flexible. That results in lower blood pressure without the side effects of
I was skeptical because I had tried other products that were
hyped as natural, safe, and effective, but none of them worked ‒ at
least not for me.
Nevertheless, the science behind this concept seemed to be
excellent ‒ in
fact a Nobel Prize had been won based on it ‒ so I decided to
give it a try.
my amazement, great results were measurable immediately. My blood pressure,
which was 170 over 94 on the day I started the trial, began dropping by about
15 points per month and didn't stop until it hit numbers I had not seen
since I was in my 20s. Currently, it is running at about 120 over 72.
UNEXPECTED BONUS BENEFITS
In 2012, when I added this product to the Reality Zone catalogue, I began received testimonials from customers who experienced a
dramatic lowering of blood pressure ‒ plus unexpected bonus
benefits, such as stabilized insulin levels (a big achievement for
diabetics), renewed sensation to feet and legs, improvement in mental clarity, reduction of varicose
veins, restoration of receding gums, protection against Alzheimer's, and
even defense against obesity.
I did not expect these
reports and, at first, it seemed unlikely that a single substance could have
a positive effect on so many unrelated disorders. The explanation, however,
turned out to be simple. The effect of nitric oxide at the cellular level is
relaxation of blood vessels and improvement of circulation ‒ which has a
beneficial effect on literally every function of life. (For an explanation
of how obesity is controlled, see the Q&A section at the bottom of this
As with most health treatments, not everyone responded the same and,
although most users had great results, some did not. It was a mystery.
the solution to the mystery was already known but was not yet applied to a
commercial product. Long ago, it was discovered that the body uses two chemical pathways to
produce nitric oxide. Sometimes this is depicted with a Ying-and-Yang
symbol, because the two paths are perceived to be a single process.
The first path was
utilized in the product I began taking
in 2012. It starts with the presence of an amino acid called L-arginine. The
second pathway, however, starts with the presence of nitrates and nitrites. One
of the differences is that the L-Arginine pathway becomes less functional as a person ages.
This is important for understanding why some people were not receiving
maximum benefit from the original product. In other words, everyone does not
follows the same path ‒ as we know so well.
INTRODUCING CARDIO MIRACLE
In 2014, the distributors of the original product
decided to incorporate these discoveries into a new formulation that follows both nitric-oxide pathways
– and they added numerous high-potency anti-oxidants to enhance the
second path. The new product is called Cardio Miracle.
This is not a mix of
patented chemicals claiming to contain "natural flavors" (which often means
more chemicals). When you read the label, shown in the FAQ section at the
end of this review, you will see that Cardio Miracle is dominantly composed
of dried, non-GMO foods. The powders are derived from real fruits and
vegetables and prepared with the absolute minimum of processing so as to
retain the original nutrients. The remaining ingredients are not just
vitamins, minerals, and enzymes, but also include natural substances that
aid the body's production of nitric oxide at the cellular level. It is truly
an impressive formulation.
I have been taking
nitric-oxide boosters since 2012
and Cardio Miracle since 2014. I am convinced that Cardio Miracle yields greater benefit
and costs less
to get that benefit
than anything before it.
You can go to the order section
THE MANY EFFECTS OF
Although my initial
interest in this product was its ability to lower blood pressure, it soon became
apparent from the testimonials we were receiving that there are many other
benefits as well – and some of them are big.
The following unsolicited letters from users tell the story.
HIGH BLOOD PRESSURE
I have been using Cardio Miracle, I have not had to take blood-pressure
medications. My pressure is now normal, and no side effects. Most of the
time I only take 1/2 dose, and it still brings it down, usually around
127/83 or so. THIS STUFF WORKS! I am a former gym rat, and Cardio Miracle
seems to tone my muscles as well. I am physically stronger with little or no
working out. "
~~ Charles Bruce
fairly young but have battled high blood pressure for over 10 years. The
medication I was on made it hard for me to do my job as a general
contractor. I started taking Cardio Miracle and started to feel better after
about a week. It's been 10 months, my doctor took me off my blood-pressure
medication, and I'm feeling better than I have in 10 years."
~~ Russell Pincock
Ed. Last week, my blood pressure was 120/68. And I am 84. Have been taking
the Cardio-Miracle that you recommended for three months. The info in your
books, The Creature from Jekyll Island and World Without Cancer, is equal to a
master's degree in sane living."
~~ Joe Ferguson, Utah.
"As a professional chemist, I began taking several of the components of
Cardio Miracle when I had a health scare involving my blood pressure and
triglycerides. Taking Cardio Miracle has made it easy, because I get
every ingredient I was taking separately, and more, in one product. I am
70-years and now feel like I am 40. I see the ingredients of Cardio
Miracle as the best of the best for my cardiovascular system and overall
CONGESTIVE HEART FAILURE
(insufficient blood flow from heart)
Heart Failure got so bad I couldn't climb a flight of stairs, I didn't
know what to do. Fortunately, a friend gave me a tub of Cardio Miracle
to try. Progressively, I began to walk up stairs with ease and was soon
able to exercise on a regular basis, completely turning my health
am so excited to endorse what this product has done for me in the last year.
I had a stroke in January, 2015, after being on an Arginine product [not
Cardio Miracle] for over 5 years. I am glad that it kept me from being
disabled, but it only had 18 ingredients. I found Cardio Miracle last April
and have been taking half as much of it [as the other product] because it
has so many other ingredients, all organic. I believe now that it has been
healing me further. We had a flood in our house in December, and I have been
able to help put down flooring, cut boards on the saw in the garage, paint
baseboards and help get them in the right place. I cooked for helpers on the
weekend and kept up almost 8 hours a day, when before I hadn't had that kind
of stamina. I am so grateful for the blessings that have come from adding
this to my daily agenda, and I only have to take half as much as I was of
the other product, so it is cheaper too!" ~~ Pat Erdman
(numbness, usually in feet and legs)
"I suffered with neuropathy in my legs and feet to the point where they
were turning dark, and my toes were turning black. I could feel nothing
from my knees down. After taking a Nitric Oxide supplement for 3 weeks,
I could feel my knees again. As I continued to take the product, the
neuropathy continued dropping. After 3 months, my feet had gone from black
to fleshy pink. I’m very grateful for Nitric Oxide giving me my life back.”
~~ Lance Voss, Hurricane, Utah
became interested in Cardio Miracle because it helped my wife with her
neuropathy. I decided I might as well take it along with her since it
couldn’t do me any harm. Then I noticed that the white biofilm coating I had
on my tongue most of my life unexplainably went away – and improved my
breath freshness. That made me happy. Since I am a dentist, I’m sure it made
my patients happy also. ~~ Gene Duffin, DDS [See
Obstructive Pulmonary Disease)
husband learned about nitric oxide in a miraculous encounter with two
strangers waiting to board a cruise last winter. They observed my husbands
pale look and labored breathing, and shared the science. He has been taking
the supplement since last April and, even with advanced COPD, his breathing
has dramatically improved, his energy level is now beyond our expectations,
and his PSA has dropped from over 10 to 2. Our doctors are shocked. We are
grateful for Cardio Miracle in our lives.”
~~ Gordon and Terri D., Norfolk, Va.
You can go to the order section
(receding or bleeding gums) and
"I have been plagued with receding gums and bleeding for over 40 years. My
dentist has recommended surgery several times along with cleanings every
three months. I tried everything I could including packing my teeth at night
with a powder to help heal the gums.
"NOTHING worked. I use a Water Pic every day and some herbal tincture, which
has helped some but never stopped the receding gums.
"After taking Cardio Miracle for three weeks; two scoops per day; I went for
my cleaning appointment and was so thrilled to hear that 17 of my pockets
had improved one to two millimeters with less bleeding than in the past.
Three months later I went back for another cleaning and was a little
nervous; fearing that the first time was just an accident! Much
to my pleasure, I had 10 more improvements of one to two millimeters in
pocket depth. Needless to say my dentist, Dr Wade, was very impressed and
said this was unheard of, wanting to hear more about the Cardio Miracle."
~~ Ray Potter, Laverkin, Utah
I read Ray Potter's testimonial, I wondered if this could be the result of
something other than Cardio Miracle, such as a change in diet or
reduction of stress. When I looked to see if there was any scientific
support for thinking nitric oxide might be responsible, I found that
researchers at State University in Rio de Janeiro, Brazil, studied that very
issue and said there was, indeed, scientific support for the theory behind
"It didn’t take long for me to schedule a dental appointment to get a
current assessment of my own periodontitis to see if Cardio Miracle made a
difference. Like Ray Potter, I was uneasy that there would be no positive
effect but, when the results were compared to my previous exam, the
improvement was nothing less than spectacular.
"My previous exam showed 69 pockets that were
deep enough to be classified as affected by periodontitis. This time, there
were only 24. That’s an amazing improvement of 65%. My hygienist,
who usually admonishes me to increase the frequency of my teeth cleaning,
studied the charts for a moment and said: 'Well, I guess this takes the
steam out of my argument.'
"Eleven months later (on 2016 April 12), when I returned for another
cleaning, the pocket count had further declined to 17. That's a 75%
improvement from what is was before taking Cardio Miracle.
This time, the hygienist asked how to obtain the product."
~~ G. Edward Griffin, Los Angeles
"Nitric oxide and oral diseases: can we talk about it?" ResearchGate.net.
"A few years ago, my dentist advised that I have periodontal disease. I
directed my research efforts to find natural remedies if possible. I tried
many things, but no calculable results. Then, relying on Mr. Griffin's recommendations, I purchased Cardio Miracle
and began using it upon arrival. I could not take two doses at first so only
took the morning dose. After about 10 days of only the morning dose, I went
to the dentist for a pre-scheduled cleaning. The hygienist was ecstatic
when, after measuring those darn pockets, many had gone from "6" to "4",
“3”, and “2”! After I told her about my Cardio usage, another patient in the
office (overhearing our conversation) insisted I give him the info on
obtaining the product – which I did. Cardio is the only thing I have tried to date that delivered positive
results for my periodontal disease. Can't tell you how much relief that
~~ Rochelle Tyler, LaGrange, Texas
Miracle brought down my blood pressure so I no longer need Statin drugs. It
brought my triglyceride levels into normal range and also boosted my
Vitamin-D levels by more than 50%. As a dentist, I am particularly impressed
by its ability to virtually eliminate periodontal disease. I now recommend
it to all my patients, most of whom report marked improvement within 60
days.” [See video]
~~ Tom Worcester, DDS, Member of the Crown Council, Florida
pain in my jaw sent me to my dentist who said I was in immediate need of a
root canal on an infected tooth. I am skeptical about the value of root
canals, so I wanted to find another solution other than tooth extraction. I
knew that Cardio Miracle was helping people with gum disease, so I decided
to see if it would help my deeply infected tooth. Swishing the formula
around the tooth for a minute before swallowing produced a sensation of
healing. After just a few days, the pain was gone. My tooth seems to be fine
now.” [See video]
`` ~~ Arlaine Austin
"We tried Cardio Miracle on a long-term patient with whom we have NEVER had
success controlling his bleeding despite using localized antibiotics,
bacterial testing and treatment, rinses, and periodontal consults. Cardio
Miracle in 90 days resulted in a reduction in his bleeding to near Zero! My
hygienist and I were astonished at how just this one supplement could make
such a difference. We will certainly be recommending Cardio Miracle to other
~~ Peter Barnett DMD, Star Ranch Dental, Plano, Texas
(For information on how Cardio Miracle combats obesity,
see the Q&A section at the bottom of this page.)
tremendous energy and I'm averaging 16,000 steps per day (as noted
by my Fit Bit) with a vigorous pace, even jogging 3+ miles each
morning. My cravings for sugary foods also seems to have decreased.
In two weeks I have lost 4.5 pounds."
~~ Dr Michael Tornow - Bloomfield, New
"90 days after starting Cardio Miracle. I've lost 23 pounds, because I have
more energy to exercise. I no longer take blood-pressure medication, and my
blood pressure reading this morning was 120/79."
~~ Greg Anderson - Salt Lake City, Utah
"Cardio Miracle is one of the few supplements that my wife and I take every
single day. The incredible benefits of nitric oxide are well known, and the
Cardio Miracle formula is superior to any formula that I have used. I
believe that everyone should be on this formula to help protect and promote
their endothelial health. In my own family, we have a history of brain
aneurysms. Cardio Miracle is my preventive nutrition to minimize that risk
for me. Highly recommended!"
Dr. Bradley Nelson, author of The Emotion Code
"If I could take one supplement and one supplement only, it would be a
nitric oxide booster."
Stephen Ashcraft, a physiologist in Nashville, Tennessee
"I take Cardio Miracle every day and have found tremendous benefits as I
participate in triathlons in my mid seventies. I wish I would have had it
years ago for my patients, as everyone needs it."
James Oury, Founder of the Missoula Heart Institute
Miracle has been the catalyst for healing my debilitating concussion.
Exercise and physical therapy were hard on my brain until I started taking
Cardio Miracle before a workout. I had an immediate result! Not only could I
exercise, my head began feeling better and my overall health improved! Thank
you Cardio Miracle!" ~~ Marci Campbell
me, Cardio Miracle has been the perfect gift. It has done more for me in one
year that medicine has done in the previous forty. The neuropathy in my
fingers and toes is gone. I sleep better. I’m healthier, stronger, have more
energy. Cardio Miracle gives me a sense of health security that I don’t get
from Big Pharma or establishment medicine." ~~ Ken Sheldon [See
"Nitric-Oxide therapy has affected my wife, Diane significantly. Her actual age 68
was a far cry from the test results (heart age 92) back in May 2011. After 8
months her heart age is now 55! Blood pressure went from 168/92 to 121/76.
In addition she was able to have carpel tunnel surgery cancelled because the
symptoms went away. Diane had a full knee replacement in 2013 and another
one in 2014. Her surgeon and physical therapist told us she recovered twice
as fast as anyone they had seen in 25 years!" ~~ Robert Haunschild.
(no photo available at present)
You can go to the order section
You can go to the order section
is the name of the taste of Cardio Miracle. You will
think you are sipping an exotic drink prepared at a beach-side
bar on a tropical island ‒ without the rum, of course. It tastes
like real fruit because that's what it is. The powders in this
product are from the real thing.
The method by which these fruits and vegetables are converted
into powder is amazing. Heating or freeze-drying food to
create dry powders destroys much of the vitamin and enzyme
content. It's a terrible loss of nutrition. However, the powders
used in Tropical Abundance are created from a process called
Infidri, which uses light waves to resonate with water molecules
and drive them out of food without damaging nutritional content
or flavor. It's an impressive technology.
All powdered foods in this process are non GMO.
Cardio Miracle contains: Beet Root powder, Carrot powder,
Coconut powder, Beet Root crystals, Pine Bark extract, Tumeric,
Grape-Seed extract, Watermelon extract, Astralagas root, Panex
Ginseng, Hawthorne Berry extract, Resveratrol, Astragin,
Astraxanthin, L-Arginine, L-Citrulline, Ornithine,
D-Ribose, Alpha Lipoic Acid, trace minerals, sea salt, CoQ10,
Pycnogenol, Selenium, Magnesium, Zinc, and a broad spectrum of
Vitamins, including D3 and K2. These often are absent even from
premium brands of multi-vitamin supplements. The full label is
shown in the Frequently-Asked Questions section.
Frequently Asked Questions
What are the
Cardio Miracle ingredients?
Here is the product
label for the sugar-free (Stevia) version:
Why isn't nitric oxide listed on the
product list of ingredients?
We apologize for not making this more clear on the product page, but
Cardio Miracle does not contain nitric oxide, which is a gas.
Instead, it contains the substances the body uses to produce nitric oxide
right inside the cells.
there a danger of Cardio Miracle overdose
leading to fatally low blood pressure?
There is no evidence of that after extensive use, but there is a theoretical concern for high-performance athletes. See
"Potentially fatal new trend in performance enhancement: a
cautionary note on nitrite," by Andrea Ptroczi and Decian P. Naughton,
Journal of the International Society of Sports Nutrition, 2010, 7:25.
How do you know that the loss of neuropathy is not merely the
It is impossible for patients to experience complete loss of
advanced neuropathy based on the placebo effect. An excellent reference
regarding the theoretical action of nitric oxide on neurons is:
Nitric Oxide and Its Role in Health and Diabetes, by Thomas
Burke, Ph.D. with special focus on Parts 5 and 8.
Is there a reliable reference for a technical description of the
Nitrate/Nitrite pathway to nitric oxide?
There are numerous studies on this topic available online. A good choice
"The nitrate-nitrite-nitric oxide pathway in physiology and therapeutics,"
by Jon O. Lundburg, Eddie Weitzberg, & Mark T. Gladwin, Nature Reviews
Drug Discovery 7,156-167 (Feb. 2008).
If L-arginine is the beginning of the chemical pathway to nitric oxide, why
does Cardio Miracle include Citrulline? What is Citrulline, anyway and what's
all the fuss about the ratio between Arginine and Citrulline?
works and what sets it
apart from others. Citrulline is
Great question for those who really want to understand how this product
Are there negative side effects from consuming sodium nitrite?
There have been studies showing a relationship between high levels of
dietary sodium nitrite and cancer. It is believed that this process is
initiated by abnormal oxidative stress. At low to moderate levels, such as
are found in Cardio Miracle, we are not aware of any such connection. It is
common for food factors to be beneficial or even essential in small quantities
but harmful in large quantities. Sodium
nitrite is an important part of Cardio Miracle because it is a precursor to
the body's production of nitric oxide, which is essential for life. However,
to be on the side of caution, the
manufacturer has added substantial levels of potent anti-oxidants to
any oxidative stress that might be present. See
"The Effects of Sodium Nitrite," by Jan Annigan, reviewed by Brenda Spriggs,
MD, MPH, MBA, Healthline, Aug. 16, 2013.
Does Cardio Miracle need to be refrigerated to keep its freshness?
No. It should be treated like a dried food, which most of it is. After
opening, it will last for several years with no problem as long as it is stored
in a cool, dry location. If atmospheric moisture causes clumping, that will not
adversely effect the product's effectiveness in any way. Clumps are easily
broken up, and the product will quickly dissolve in water or juice as before.
Are there any special discounts on this product for Reality Zone customers?
Due to improved product ingredients and inflation, the increased cost of Cardio
Miracle has required that all special discounts for special groups be ended.
Discounts may be issued in the future on special occasions but will have
specific ending dates.
For cardiovascular benefit, why not just take Viagra as it's cheaper and probably more effective?
The answer to this is provided by Stephen Ashcraft,
a physiologist in Nashville, Tennessee. [mailto:email@example.com]
"To understand how Viagra works, we
must first understand what physiological
response causes an erection. The body releases Nitric Oxide (NO) when we are sexual stimulated. This NO
release comes from nerve endings and endothelial cells in the corpus cavernosum of the penis and clitoris. An enzyme then converts guanosine
triphosphate (GTP) into cyclic guanosine monophosphate (cGMP). cGMP then
causes the smooth muscle of the vessels in the penis, or clitoris, to relax,
which then allows for a greater inflow of blood which then leads to an
erection. cGMP is then hydrolyzed back to the inactive GMP by
phosphodiesteras type 5, also known as PDE5.
"We know that most Men who suffer from erectile dysfunction do not produce
enough NO. This is why we can say that erectile dysfunction is one of the
earliest visible responses to cardio vascular disease. Because of low NO
production in these men, the small amount of cGMP they produce is broken
down at the same rate and therefore doesn't have the time required, to
accumulate, and cause a prolonged vasodilatation effect, the erection.
"Sildenafil (Viagra) is a potent and highly selective inhibitor of PDE5. Sildenafil
(Viagra) works by inhibiting the enzyme PDE5 (phosphodiesteras). This means
that cGMP is not hydrolyzed as fast and this allows the vessel smooth muscle
1. Viagra does not increase NO production, thus one would not receive the
numerous benefits, to the cardiovascular system, of NO.
2. Viagra has numerous negative side effects.
3. PDE5 function is specific to the penis and clitoris.
4. The response is short lived and not recommended for using multiple doses
"Cardio Miracle provides a consistent elevation of NO, thus causing the
vascular system to function as it is suppose to, dilating and constricting
according to cardiac output and increased stroke volume. Neither Viagra nor its
competitor drugs provide this response. Erectile Dysfunction has been
shown in research to diminish with greater NO production."
A respected alternative-medicine doctor has said in his newsletter that
supplemental L-arginine is a poor source for increasing nitric oxide, and
possibly does not work at all. If this is true, why is it in Cardio Miracle?
for the answer:
Again, we will defer to Stephen Ashcraft
"There are several, obvious, issues with this article. First, [the doctor] is selling another product, one he claims works better for
NO production than L-arginine. Rather than argue the point, I would simply
refer him, or any other inquisitive person, to the hundreds if not
thousands of clinical trials proving the effectiveness of L-arginine as a
precursor and producer of NO. Furthermore, I would remind him, and others,
the 1998 Noble Prize Winner, for medicine, Dr. Louis Ignarro, won the Noble
Prize for discovering NO. Dr. Ignarro went on, in his book "No More Heart
Disease," to explain in great detail the benefits of L- arginine.
"Second, the [doctor's] article is correct in that oral L-arginine does convert to urea.
It also converts to NO, ornithine, and agmatine. ... Many of the health benefits, from L-arginine, can be
attributed to the fact that some of the L-arginine converts to urea. Urea
has many health benefits. It supports protein synthesis, thus its importance
for patients suffering from kidney failure, kidney infections, and for athletes
who are wanting to gain greater muscle mass. Urea is also the best diuretic,
and has proven helpful with brain tumors, strokes, meningitis and other
inflammations of the brain and spinal cord. One report cites the case of a
massive brain tumor reappearing 3 months after surgical removal of another
brain tumor. The patient received 256ml of 30% urea. After 2 hours the tumor had completely disappeared. Urea is also very beneficial in wound
healing, even infected wounds, burns and ulcerating tumors. Urea is one of
the main reasons L-arginine, converting to NO, is such a powerful recovery
agent. Urea greatly reduces exercise recovery time by removing ammonia, a
by-product of lactic acid, which occurs from repetitive muscular
contractions. So, while it is certainly true that some of the L-arginine
converts to urea, it is also a good thing.
"Also, it is true that L-arginine can be very difficult to
assimilate. Studies have shown that our bodies utilize less than 50% of the
L-arginine we consume. This means that you can't digest and use L-arginine
efficiently. It is for this reason, that hospitals, and many researchers use
intravenous arginine injection instead of oral doses. The Cardio Miracle
solution to this problem is a different form of arginine called, L-arginine AAKG (alpha-ketoglutarate). AAKG has been shown to have a 90% utilization
rate. Also, by adding the amino acid, L-citrulline, and other active NO
boosters, you can greatly enhance the effectiveness of L-arginine conversion
in the NOS pathway. Furthermore, the pharmaceutical grade AAKG form of
L-arginine gives the endothelium support and vaso-relaxation properties of
arginine, plus greater arginine stability, bioavailability, and absorption.
If that's not enough, the AAKG serves as a transport medium for arginine,
thus making it available at the cellular level for optimal synthesis. AAKG
will also improve endogenous production of glutamine and glutamic acid, both
of which are important for muscle growth.
"Another noteworthy fact of Cardio Miracle is the dual-pathway of delivery.
The two primary ways our bodies generate and deliver NO are: (1) the enzymatic
process that oxidizes a nitrogen atom in the amino acid, arginine, to nitric
oxide. This process is known as the arginine-nitric oxide pathway. Arginine
is converted to NO by the endothelium. L-citrulline, also used in the Cardio
Miracle formula, is another amino acid and can also be converted into NO by
means of the same pathway. (2) The second pathway is a non-enzymatic process
where nitrites and nitrates, which are naturally occurring, are converted to
NO either by bacteria in the intestine and mouth, or by naturally occurring
antioxidants. Some fruits and roots are converted into NO via this same
pathway. By taking advantage of both pathways, and adding additional NO
boosters, Cardio Miracle extends the active life of NO, in the system.
"NO can oxidize and become a free radical. Cardio Miracle is loaded with
some of the most powerful antioxidants known that lower homocysteine levels and inhibit the oxidation process. Another way of
eliminating any concern of the free radical issue is the NO loop. By
combining other key NO precursors a loop is created, thereby protecting the
NO from becoming a free radical, and greatly extending the life of NO.
"Most NO boosters, on the market, rely on L-arginine as their primary source
for NO. A few, and I mean a very few, will use some L-citrulline; and even
fewer will use AAKG. As we've already mentioned, there are a number of
sources of NO production. NOS occurs through several different pathways,
thus Cardio Miracle, a product that actually works, uses multiple pathways
of delivery. Because Cardio Miracle contains multiple sources of NO
precursors, and multiple pathways of delivery, it contains a lower dose of
L-arginine, and also greatly enhance the health benefits of NO."
What are endothelial progenitor cells, and what do they have to do with
Endothelial refers to a layer of cells that line the inner walls of
the circulatory system, everything from the heart to the smallest
capillaries. Their function is to pass nutrients from the bloodstream into
the organs ‒ and pass waste products in the opposite direction where they
are carried to the liver and kidneys for disposal. Since all functions of
life depend on that process, healthy endothelial cells are essential for
health and youth.
The bad news is that endothelial cells have a life span of only a few years
(even shorter when exposed to toxins from drugs, processed food, and
contaminated air). The good news is that the body is able to replace those
dying endothelial cells with new ones. That's where the word progenitor
comes into play. It refers to a stem cell that is programmed by its DNA
to morph into a specialized cell that can replace an aging or damaged cell.
Therefore, endothelia progenitor cells (EPCs) gradually become new
The bad news, however, is that the body's ability to produce EPCs diminishes
with age, which is a major cause of declining health and vigor as we grow
older. But the final good news is that researchers recently have discovered
a way, not only to increase the body's production of EPCs, which occurs in
bone marrow, but to send them to precise locations in the cardio-vascular
system that need them the most ‒ and it does this regardless of age. (See
Nitric oxide differentially regulates proliferation
and mobilization of endothelial progenitor cells but not of hematopoietic
stem cells. Ozüyaman B1, Ebner P, Niesler U, Ziemann J, Kleinbongard P,
Jax T, Gödecke A, Kelm M, Kalka,
Cardio Miracle stimulates the body to increase its own, natural production
of nitric oxide ‒ and that is the substance that stimulates the production
How does Cardio Miracle combat obesity?
Most of the benefits of Cardio Miracle can be understood as the result of
improved circulation and oxygenation, but combating obesity is related to a
biological process called mitochondrial biogenesis. Don’t be intimidated by
the words. They simply mean the body’s production of a component of all
cells (the mitochondria) that converts nutrients derived from food into
energy. Mitochondrial biogenesis also is dependent on oxygenation, but its
function is related to the accumulation of body fat.
An efficient mitochondria readily converts nutrients derived from food into
energy, and only excess food consumption is left over for fat. If the
mitochondria are not efficient, the conversion to energy will be impaired, a
condition called low metabolism. This causes low energy levels ‒ manifested
as weakness and fatigue ‒ and increased fat formation.
Many things can reduce the function of mitochondria, everything from
enzymatic dysfunction to toxins to aging. Therefore, anything that supports
the maintenance of healthy mitochondria will combat obesity ‒ especially if
related to low metabolism.
The effect of nitric oxide on diabetes was the topic of a 2014 study by
Brian Sansbury and Bradford Hill.(1) They found that nitric oxide does help
control diabetes, but it does so because of how it combats obesity:
reduces insulin resistance.
● It regulates appetite.
It supports the production and efficiency of mitochondria.
researchers stated: "Overall, the collective data suggest that L-arginine,
and by inference, NO [nitric oxide], has the capacity to reduce fat mass by
increasing mitochondrial biogenesis, regulating brown adipose tissue
signaling, and increasing the expression of genes that promote oxidation of
laymen’s terms, that means: Nitric Oxide
(which is produced by the body in response to
the dietary presence of an amino acid called L-Arginine)
reduces fat by decreasing appetite and increasing
the body’s ability to convert food into energy.
(1) "Regulation of Obesity and Insulin Resistance by Nitric
Oxide", by Brian E. Sansbury1 and Bradford G. Hill1, Science Direct,
Free Radical Biology and Medicine, Vol 73, August 2014. pp. 382-399.
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4112002/ This paper also
contains an excellent overview of many other health effects of ample
Letter received 2016 Sept. 19 from Mike:
"A product called Cardio for Life is half the price of Cardio Miracle and
twice the benefits."
We sent Mike’s letter to John Hewlett for comment. John is the
formulator of Cardio Miracle.
Letter received 2016 Sep. 22 from John Hewlett:
“I have some experience with Cardio for Life. Dr Elwardt (who formulated it)
wrote a good book a number of years ago on the topic, and it is a nice
product. It is sold through a five-level MLM program. It sells [as of 2016]
for $59.95 for 30 servings. Being a distributor can get the price down to
$39.95 for 30 servings, which is $2.00 a serving down to $1.33, and can get
lower if you buy 6 canisters at a time. Cardio miracle in several of our
packages, is $1.50 a serving, down to around a $1.20 on some specials, so
Cardio for Life definitely is not half price.
“As far as twice the benefit, the science will not back up that claim. Both
products have arginine, and astragin. Cardio Miracle has substantially more
citrulline, watermelon extract, and pre and probiotics, which extend nitric
oxide. We have substantially more antioxidants, anti inflammatories, and
organic powders, including beet root, carrot, and coconut water, which have
cutting edge benefits. We have over 50 ingredients in meaningful quantities.
Cardio for Life, has less than 20.
“It is always happy news to learn that someone has good results from a lower
potency product. That is to be expected because, in many cases, just a
little more cellular nitric oxide is sufficient to bring about a spectacular
benefit. However, in any reasonable comparison, the claim of half-price and
twice-the-benefit probably is driven by a committed distributor who likes
his product, but the facts don't quite live up to the claim. In all areas,
Cardio Miracle is the cutting edge of dual pathway nitric oxide delivery at
the lowest price for the potency it delivers.
“Incidentally, Dr. Joseph Prendergast (retired Medical Director of the
Endocrine Metabolic Medical Center, Palo Alto, California) was a mentor to
Dr Elwardt. Dr. Prendergast, who has more experience with patients and
nitric oxide than anyone I know, now takes Cardio Miracle without
compensation from us and recommends it as the best product he has ever
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